Artiklar / Articles - K1 (MMK): Recent submissions
Now showing items 61-80 of 91
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The surgical management of esophago-gastric junctional cancer
(Inst för molekylär medicin och kirurgi / Dept of Molecular Medicine and Surgery, 2016-10-11)The best available surgical strategy in the treatment of resectable esophago-gastric junctional (EGJ) cancer is a controversial topic. In this review we evaluate the current literature and scientific evidence examining the ... -
Common genetic variations in cell cycle and DNA repair pathways associated with pediatric brain tumor susceptibility
(Institutet för miljömedicin / Institute of Environmental Medicine, 2016-10-05)Knowledge on the role of genetic polymorphisms in the etiology of pediatric brain tumors (PBTs) is limited. Therefore, we investigated the association between single nucleotide polymorphisms (SNPs), identified by candidate ... -
Mortality from laparoscopic antireflux surgery in a nationwide cohort of the working-age population
(Inst för molekylär medicin och kirurgi / Dept of Molecular Medicine and Surgery, 2016-09-29)Background: Effective treatment of severe gastro-oesophageal reflux disease is available through medication or surgery. Postoperative risks have contributed to decreased use of antireflux surgery. We aimed to assess ... -
Weekday of oesophageal cancer surgery in relation to early postoperative outcomes in a nationwide Swedish cohort study
(Inst för molekylär medicin och kirurgi / Dept of Molecular Medicine and Surgery, 2016-06-22)Objectives: Later weekday of surgery for oesophageal cancer seems to increase 5-year mortality, but the mechanisms are unclear. We hypothesised that early postoperative reoperations and mortality might explain this ... -
Using the Lorenz curve to assess the feasibility of targeted screening for esophageal adenocarcinoma
(Inst för molekylär medicin och kirurgi / Dept of Molecular Medicine and Surgery, 2016-06-22) -
A multimodal brain imaging dataset on sleep deprivation in young and old humans
(Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2016-05-26)The Stockholm Sleepy Brain Study I is a functional brain imaging study of 48 younger (20-30 years) and 36 older (65-75 years) healthy participants, with magnetic resonance imaging after normal sleep and partial sleep ... -
A global assessment of the male predominance in esophageal adenocarcinoma
(Inst för molekylär medicin och kirurgi / Dept of Molecular Medicine and Surgery, 2016-05-09)Background: Esophageal adenocarcinoma (EAC) is characterized by a male predominance. However, variations in the sex difference across populations and over time have not previously been thoroughly investigated. Results: ... -
Antireflux surgery and risk of esophageal adenocarcinoma : a systematic review and meta-analysis
(Inst för molekylär medicin och kirurgi / Dept of Molecular Medicine and Surgery, 2016-04-05)Objective: To investigate the preventive effect of antireflux surgery against esophageal adenocarcinoma (EAC), compared to medical treatment of gastroesophageal reflux disease (GERD) and to the background population. ... -
Esophageal adenocarcinoma after obesity surgery in a population-based cohort study
(Inst för molekylär medicin och kirurgi / Dept of Molecular Medicine and Surgery, 2016-03-18)Background: Obesity is strongly associated with esophageal adenocarcinoma (EAC), yet whether weight loss reduces the risk of EAC is unclear. Objectives: To test the hypothesis that the risk of EAC decreases following ... -
Intermittent pneumatic compression reduces the risk of deep vein thrombosis during post-operative lower limb immobilisation : a prospective randomised trial of acute ruptures of the Achilles tendon
(Inst för molekylär medicin och kirurgi / Dept of Molecular Medicine and Surgery, 2016-01-20)Deep vein thrombosis is a common complication when immobilising the lower limb after surgery. We hypothesised that adjuvant intermittent pneumatic compression (IPC) during post-operative outpatient immobilisation of the ... -
Neuronal pathways in tendon healing and tendinopathy : update
(Inst för molekylär medicin och kirurgi / Dept of Molecular Medicine and Surgery, 2016-01-19)The regulatory mechanisms involved in tendon homeostasis and repair are not fully understood. Accumulating data, however, demonstrate that the nervous system, in addition to afferent (sensory) functions, through efferent ... -
Extent of lymphadenectomy and prognosis after esophageal cancer surgery
(Inst för molekylär medicin och kirurgi / Dept of Molecular Medicine and Surgery, 2015-10-02)Importance: The prognostic role of the extent of lymphadenectomy during surgery for esophageal cancer is uncertain and requires clarification. Objective: To clarify whether the number of removed lymph nodes influences ... -
Gastroesophageal reflux does not alter effects of body mass index on risk of esophageal adenocarcinoma
(Inst för molekylär medicin och kirurgi / Dept of Molecular Medicine and Surgery, 2015-10-02)Background & Aims: A history of high body mass index (BMI) is strongly associated with risk of esophageal adenocarcinoma (EAC). We investigated whether gastroesophageal reflux is involved in this association. Methods: ... -
Weekday of esophageal cancer surgery and its relation to prognosis
(Inst för molekylär medicin och kirurgi / Dept of Molecular Medicine and Surgery, 2015-10-02)In this nationwide Swedish study, later weekday of esophageal cancer surgery entailed increased long-term mortality, particularly for earlier tumor stages. The increase in 5-year mortality for each later weekday was 7% for ... -
Education level influences long-term survival after esophageal cancer surgery in a nationwide Swedish cohort study
(Inst för molekylär medicin och kirurgi / Dept of Molecular Medicine and Surgery, 2015-09-22)Objectives: This study aimed to investigate whether a higher education level is associated with an improved long-term survival after oesophagectomy for cancer. Design: A prospective, population-based cohort ... -
What is the most effective treatment for severe gastro-oesophageal reflux disease?
(Inst för molekylär medicin och kirurgi / Dept of Molecular Medicine and Surgery, 2015-06-26)This is one of a series of occasional articles that highlight areas of practice where management lacks convincing supporting evidence. The series adviser is David Tovey, editor in chief, the Cochrane Library. -
Early complications following oesophagectomy for cancer in relation to long-term healthcare utilisation: a prospective population-based cohort study
(Inst för molekylär medicin och kirurgi / Dept of Molecular Medicine and Surgery, 2015-03-16)BACKGROUND: Little is known about how early postoperative complications after oesophagectomy for cancer influence healthcare utilisation in the long-term. We hypothesised that these complications also increase healthcare ... -
Tumour staging of oesophageal cancer in the Swedish Cancer Registry : a nationwide validation study
(Inst för molekylär medicin och kirurgi / Dept of Molecular Medicine and Surgery, 2015-03-12)Background: Tumour stage was introduced to the Swedish Cancer Registry in 2004, but this key variable for prognostic research has not yet been validated. We validated the tumour stage data in surgically treated oesophageal ... -
Hospital and surgical volume in relation to long-term survival after oesophagectomy : systematic review and meta-analysis
(Inst för molekylär medicin och kirurgi / Dept of Molecular Medicine and Surgery, 2015-03-11)BACKGROUND: Centralisation of healthcare, especially for advanced cancer surgery, has been a matter of debate. Clear short-term mortality benefits have been described for oesophageal cancer surgery conducted at high-volume ... -
Marital status and survival after oesophageal cancer surgery : a population-based nationwide cohort study in Sweden
(Inst för molekylär medicin och kirurgi / Dept of Molecular Medicine and Surgery, 2015-03-11)Objectives A beneficial effect of being married on survival has been shown for several cancer types, but is unclear for oesophageal cancer. The objective of this study was to clarify the potential influence of the marital ...