Artiklar / Articles - K1 (MMK): Recent submissions
Now showing items 41-60 of 91
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Increased cardiovascular and metabolic morbidity in patients with 21-hydroxylase deficiency : a Swedish population-based national cohort study
(Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2017-03-29)CONTEXT: Congenital adrenal hyperplasia (CAH) is lethal in its most severe forms if not treated with glucocorticoids. However, glucocorticoids may increase the risk of cardiovascular and metabolic morbidity. OBJECTIVE: ... -
Increased mortality in patients with congenital adrenal hyperplasia due to 21-hydroxylase deficiency
(Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2017-03-20)Context: Reports on mortality in patients with congenital adrenal hyperplasia (CAH) are lacking. Objective: To study mortality and causes of death in CAH. Design, Setting and Participants: We studied patients ... -
Time trends in the incidence of oesophageal cancer in Asia : variations across populations and histological types
(Inst för molekylär medicin och kirurgi / Dept of Molecular Medicine and Surgery, 2017-03-14)OBJECTIVE: We aimed to assess temporal trends in incidence rates of oesophageal cancer in Asian countries. MATERIALS AND METHODS: Using data from the Cancer Incidence in Five Continents series, we examined the ... -
The male predominance in esophageal adenocarcinoma
(Inst för molekylär medicin och kirurgi / Dept of Molecular Medicine and Surgery, 2017-02-21)The incidence of esophageal adenocarcinoma (EAC) has increased rapidly during the past four decades in many Western populations, including North America and Europe. The established etiological factors for EAC include ... -
A model for predicting individuals' absolute risk of esophageal adenocarcinoma : moving toward tailored screening and prevention
(Inst för molekylär medicin och kirurgi / Dept of Molecular Medicine and Surgery, 2017-02-15)Esophageal adenocarcinoma (EAC) is characterized by rapidly increasing incidence and poor prognosis, stressing the need for preventive and early detection strategies. We used data from a nationwide population-based ... -
Sequencing-based breast cancer diagnostics as an alternative to routine biomarkers
(Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2017-01-16)Sequencing-based breast cancer diagnostics have the potential to replace routine biomarkers and provide molecular characterization that enable personalized precision medicine. Here we investigate the concordance between ... -
Snus and risk of gastroesophageal reflux : a population-based case-control study : the HUNT study
(Inst för molekylär medicin och kirurgi / Dept of Molecular Medicine and Surgery, 2017-01-04)Objective: Tobacco smoking is a risk factor for gastroesophageal reflux, but whether other tobacco products increase the risk is unclear. The aim of this study was to investigate if snus increases the risk of gastroesophageal ... -
Risk factors of admission for acute colonic diverticulitis in a population-based cohort study : the HUNT Study, Norway
(Inst för molekylär medicin och kirurgi / Dept of Molecular Medicine and Surgery, 2017-01-04)AIM: To assess risk factors of hospital admission for acute colonic diverticulitis. METHODS: The study was conducted as part of the second wave of the population-based North Trondelag Health Study (HUNT2), performed ... -
Metabolic syndrome and esophageal and gastric cancer
(Inst för molekylär medicin och kirurgi / Dept of Molecular Medicine and Surgery, 2016-12-20)BACKGROUND: The role of the metabolic syndrome in the etiology of esophageal and gastric cancer is unclear. METHODS: This was a large nationwide cohort study based on data from 11 prospective population-based cohorts ... -
Anthropometry-based obesity phenotypes and risk of colorectal adenocarcinoma : a large prospective cohort study in Norway
(Inst för molekylär medicin och kirurgi / Dept of Molecular Medicine and Surgery, 2016-12-20)BACKGROUND: It is unclear whether obesity phenotypes measured by different anthropometric indices are associated with a risk of colorectal adenocarcinoma by anatomical location. METHODS: We compiled harmonized ... -
Metabolic predispositions and increased risk of colorectal adenocarcinoma by anatomical locations : a large population-based cohort study in Norway
(Inst för molekylär medicin och kirurgi / Dept of Molecular Medicine and Surgery, 2016-12-19)Whether different definitions of metabolic syndrome (MetS) are differently associated with colorectal adenocarcinoma (CA) by anatomical location is unclear. A population-based cohort study, the Cohort of Norway (CONOR) ... -
Risk factors on the development of new-onset gastroesophageal reflux symptoms : a population-based prospective cohort study : the HUNT study
(Inst för molekylär medicin och kirurgi / Dept of Molecular Medicine and Surgery, 2016-12-19)OBJECTIVES: Gastroesophageal reflux disease (GERD) is a highly prevalent disorder. This study assessed the risk factors of new-onset gastroesophageal reflux symptoms (GERS). METHODS: The study was based on the HUNT ... -
Risk factors of having cholecystectomy for gallstone disease in a prospective population-based cohort study
(Inst för molekylär medicin och kirurgi / Dept of Molecular Medicine and Surgery, 2016-12-16)BACKGROUND: The relationship between different lifestyle factors and the risk of needing cholecystectomy for gallstone disease is not clear. This study aimed to assess the association between anthropometric, lifestyle and ... -
Weight loss and reduction in gastroesophageal reflux : a prospective population-based cohort study : the HUNT study
(Inst för molekylär medicin och kirurgi / Dept of Molecular Medicine and Surgery, 2016-12-16)OBJECTIVES: High body mass index (BMI) is an established risk factor of gastroesophageal reflux symptoms (GERS). The aim of this study was to clarify if weight loss reduces GERS. METHODS: The study was part of the ... -
Changes in prevalence, incidence and spontaneous loss of gastro-oesophagealreflux symptoms : a prospective population-based cohort study, the HUNT study
(Inst för molekylär medicin och kirurgi / Dept of Molecular Medicine and Surgery, 2016-12-16)OBJECTIVE: Changes in the occurrence of gastro-oesophageal reflux symptoms (GORS) in the population remain uncertain. This study aimed to determine the prevalence changes, the incidence and the spontaneous loss of ... -
Lifestyle intervention in gastroesophageal reflux disease
(Inst för molekylär medicin och kirurgi / Dept of Molecular Medicine and Surgery, 2016-12-16)BACKGROUND & AIMS: Gastroesophageal reflux disease (GERD) affects up to 30% of adults in Western populations and is increasing in prevalence. GERD is associated with lifestyle factors, particularly obesity and tobacco ... -
Tobacco smoking cessation and improved gastroesophageal reflux : a prospective population-based cohort study : the HUNT study
(Inst för molekylär medicin och kirurgi / Dept of Molecular Medicine and Surgery, 2016-12-12)Objective: Tobacco smoking increases the risk of gastroesophageal reflux symptoms (GERS), but whether tobacco smoking cessation improves GERS is unclear. The aim of this study was to clarify if tobacco smoking cessation ... -
Longitudinal fluctuation in mammographic percent density differentiates between interval and screen-detected breast cancer
(Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2016-11-29)Interval breast cancer (IC) has a more aggressive phenotype and higher mortality than screen-detected cancer (SDC). In this case-case study, we investigated whether the size of longitudinal fluctuations in mammographic ... -
Colorectal cancer prognosis following obesity surgery in a population-based cohort study
(Inst för molekylär medicin och kirurgi / Dept of Molecular Medicine and Surgery, 2016-11-28)BACKGROUND: Obesity surgery involves mechanical and physiological changes of the gastrointestinal tract that might promote colorectal cancer progression. Thus, we hypothesised that obesity surgery is associated with poorer ... -
A possible link between famine exposure in early life and future risk of gastrointestinal cancers : implications from age-period-cohort analysis
(Inst för molekylär medicin och kirurgi / Dept of Molecular Medicine and Surgery, 2016-10-27)The Chinese famine in 1958-1962 was one of the worst in human history, but its potential influence on cancer risks is uncertain. Using cancer incidence data in Shanghai, China, during 1983-2007, we calculated age-specific ...