Artiklar / Articles - K1 (MMK): Recent submissions

Now showing items 81-91 of 91

    • Education level and survival after esophageal cancer surgery : a prospective population-based cohort study 

      Brusselaers, Nele; Ljung, Rickard; Mattsson, Fredrik; Johar, Asif; Wikman, Anna; Lagergren, Pernilla; Lagergren, Jesper (Inst för molekylär medicin och kirurgi / Dept of Molecular Medicine and Surgery, 2015-03-10)
      Objectives: This study aimed to investigate whether a higher education level is associated with an improved long-term survival after oesophagectomy for cancer. Design: A prospective, population-based cohort ...

    • Presence of symptom clusters in surgically treated patients with esophageal cancer 

      Wikman, Anna; Johar, Asif; Lagergren, Pernilla (Inst för molekylär medicin och kirurgi / Dept of Molecular Medicine and Surgery, 2015-03-04)
      BACKGROUND: It is not known whether symptoms cluster together after esophageal cancer surgery or whether such symptom clusters are associated with survival in patients with esophageal cancer who are treated surgically. ...

    • Hypospadias and increased risk for neurodevelopmental disorders 

      Butwicka, Agnieszka; Lichtenstein, Paul; Landén, Mikael; Nordenvall, Anna Skarin; Nordenström, Anna; Nordenskjöld, Agneta; Frisén, Louise (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2014-07-31)
      BACKGROUND: Hypospadias (aberrant opening of the urethra on the underside of the penis) occurs in 1 per 300 newborn boys. It has been previously unknown whether this common malformation is associated with increased psychiatric ...

    • Suboptimal psychosocial outcomes in patients with congenital adrenal hyperplasia : epidemiological studies in a nonbiased national cohort in Sweden 

      Strandqvist, Anna; Falhammar, Henrik; Lichtenstein, Paul; Hirschberg, Angelica L; Wedell, Anna; Norrby, Christina; Nordenskjöld, Agneta; Frisén, Louise; Nordenström, Anna (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2014-06-13)
      Context: Congenital adrenal hyperplasia (CAH), CYP21A2 deficiency, results in cortisol and aldosterone deficiency and increased production of androgens, with a good genotype phenotype correlation. Objective: To study ...

    • Development of classical Hodgkin’s lymphoma in an adult with biallelic STXBP2 mutations 

      Machaczka, Maciej; Klimkowska, Monika; Chiang, Samuel C C; Meeths, Marie; Müller, Martha-Lena; Gustafsson, Britt; Henter, Jan-Inge; Bryceson, Yenan T (Inst för medicin, Huddinge / Dept of Medicine, Huddinge, 2013-07-31)
      Experimental model systems have delineated an important role for cytotoxic lymphocytes in the immunosurveillance of cancer. In humans, perforin-deficiency has been associated with occurrence of hematologic malignancies. ...

    • Clinical implementation of a new antibiotic prophylaxis regimen for percutaneous endoscopic gastrostomy 

      Lagergren, Jesper; Mattsson, Fredrik; Lagergren, Pernilla (Inst för molekylär medicin och kirurgi / Dept of Molecular Medicine and Surgery, 2013-07-04)
      OBJECTIVES: This study was undertaken to test the extent to which a new antibiotic prophylaxis regimen for percutaneous endoscopic gastrostomy (PEG), identified as a justified and simpler alternative to conventional regimen ...

    • Abdominal fat and male excess of esophageal adenocarcinoma 

      Lagergren, Katarina; Mattsson, Fredrik; Lagergren, Jesper (Inst för molekylär medicin och kirurgi / Dept of Molecular Medicine and Surgery, 2013-04-12)
      The 7-to-1 male-to-female ratio in esophageal and gastroesophageal junctional adenocarcinoma (EAC) might be explained by abdominal adiposity, typical for males. If true, a stronger male predominance in higher BMI categories ...

    • Emotional distress : a neglected topic among surgically treated oesophageal cancer patients 

      Wikman, Anna; Smedfors, Gabriella; Lagergren, Pernilla (Inst för molekylär medicin och kirurgi / Dept of Molecular Medicine and Surgery, 2013-03-27)

    • Analysis of colorectal cancer morpohology in relation to sex, location and family history 

      Ghazi, Sam; Lindforss, Ulrik; Lindberg, Greger; Berg, Elisabeth; Lindblom, Annika; Papadogiannakis, Nikos; The Low-Risk Colorectal Cancer Study Group (Inst för molekylär medicin och kirurgi / Dept of Molecular Medicine and Surgery, 2013-02-13)
      Background: Studies of colorectal cancer (CRC) have suggested different mechanisms of carcinogenesis in men and women, young and old patients, right- and left sided tumors, and sporadic and familial tumors. These differences ...

    • Cumulative impact of 10 common genetic variants on colorectal cancer risk in 42,333 individuals from eight populations 

      Dunlop, Malcolm G; Tenesa, Albert; Farrington, Susan M; Ballereau, Stephane; Brewster, David H; Koessler, Thibaud; Pharoah, Paul; Schafmayer, Clemens; Hampe, Jochen; Voelzke, Henry; Chang-Claude, Jenny; Hoffmeister, Michael; Brenner, Hermann; von Holst, Susanna; Picelli, Simone; Lindblom, Annika; Jenkins, Mark A; Hopper, John L; Casey, Graham; Duggan, David J; Newcomb, Polly A; Abuli, Anna; Bessa, Xavier; Ruiz-Ponte, Clara; Castellvi-Bel, Sergi; Niittymaeki, Iina; Tuupanen, Sari; Karhu, Auli; Aaltonen, Lauri A; Zanke, Brent; Hudson, Tom; Gallinger, Steven; Barclay, Ella; Martin, Lynn; Gorman, Maggie; Carvajal-Carmona, Luis G; Walther, Axel; Kerr, David J; Lubbe, Steven; Broderick, Peter; Chandler, Ian; Pittman, Alan; Penegar, Steven; Campbell, Harry; Tomlinson, Ian; Houlston, Richard S (Inst för molekylär medicin och kirurgi / Dept of Molecular Medicine and Surgery, 2013-02-07)
      OBJECTIVE: Colorectal cancer (CRC) has a substantial heritable component. Common genetic variation has been shown to contribute to CRC risk. A study was conducted in a large multi-population study to assess the feasibility ...

    • Common variation near CDKN1A, POLD3 and SHROOM2 influences colorectal cancer risk 

      Dunlop, Malcolm G; Dobbins, Sara E; Farrington, Susan M; Jones, Angela M; Palles, Claire; Whiffin, Nicola; Tenesa, Albert; Spain, Sarah; Broderick, Peter; Ooi, Li-Yin; Domingo, Enric; Smillie, Claire; Henrion, Marc; Frampton, Matthew; Martin, Lynn; Grimes, Graeme; Gorman, Maggie; Semple, Colin; Ma, Yusanne P; Barclay, Ella; Prendergast, James; Cazier, Jean-Baptiste; Olver, Bianca; Penegar, Steven; Lubbe, Steven; Chandler, Ian; Carvajal-Carmona, Luis G; Ballereau, Stephane; Lloyd, Amy; Vijayakrishnan, Jayaram; Zgaga, Lina; Rudan, Igor; Theodoratou, Evropi; Colorectal Tumour Gene Identification (CORGI) Consortium; Starr, John M; Deary, Ian; Kirac, Iva; Kovacevic, Dujo; Aaltonen, Lauri A; Renkonen-Sinisalo, Laura; Mecklin, Jukka-Pekka; Matsuda, Koichi; Nakamura, Yusuke; Okada, Yukinori; Gallinger, Steven; Duggan, David J; Conti, David; Newcomb, Polly A; Hopper, John L; Jenkins, Mark A; Schumacher, Fredrick; Casey, Graham; Easton, Douglas; Shah, Mitul; Pharoah, Paul; Lindblom, Annika; Liu, Tao; Swedish Low-Risk Colorectal Cancer Study Group; Smith, Christopher G; West, Hannah; Cheadle, Jeremy P; COIN Collaborative Group; Midgley, Rachel; Kerr, David J; Campbell, Harry; Tomlinson, Ian; Houlston, Richard S (Inst för molekylär medicin och kirurgi / Dept of Molecular Medicine and Surgery, 2013-02-07)
      We performed a meta-analysis of five genome-wide association studies to identify common variants influencing colorectal cancer (CRC) risk comprising 8,682 cases and 9,649 controls. Replication analysis was performed in ...