Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience: Recent submissions
Now showing items 41-60 of 781
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The pill and the will : pharmacological and psychological modulation of cognitive and affective processes
(Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2023-05-22)Background: Impairments in cognition are components of practically all psychiatric disorders and in that sense transdiagnostic factors. In both clinical and non-clinical populations, ‘hot’ and ‘cold’ cognitive control, ... -
Cannabis use in adolescence : studies of trends, correlates and adverse mental health consequences
(Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2023-05-11)Background: Cannabis is currently the most commonly used illicit psychoactive substance. Cannabis use is typically initiated during adolescence and is more common among young people than among adults. Cannabis use is ... -
Brain imaging of chronic pain : from the association with immune mechanisms to brain networks
(Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2023-05-10)Musculoskeletal chronic pain encompasses the two mechanistically distinct categories of nociplastic pain and nociceptive pain. The former is classically typified by fibromyalgia whereas the latter is characteristic of ... -
Obsessive-compulsive disorder : novel insights on executive functions, gut microbiome, and genetics
(Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2023-05-10)Background: Obsessive-compulsive disorder (OCD) is characterized by intrusive thoughts and images, and repetitive, time-consuming compulsions. It causes disability and impaired quality of life. The neurobiological model ... -
Sickness absence and disability pension among injured bicyclists and pedestrians
(Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2023-05-04)Background: Active transportation such as walking and bicycling provides an opportunity for individuals to incorporate physical activity into daily life. It has a positive impact on public health and is an important aspect ... -
Alcohol-related harm among youth in Sweden
(Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2023-05-02)Background: Compared to before the turn of the millennium, adolescents are now less likely to drink alcohol and to engage in heavy episodic drinking, both in Sweden and in many other countries. However, in societies where ... -
Deciphering and fine-tuning of myeloid cells in CNS demyelinating conditions
(Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2023-04-21)Demyelination in the central nervous system (CNS) is a characteristic of various neurological disorders, such as multiple sclerosis (MS), neuromyelitis optica (NMO), subacute combined degeneration (SCD), tabes dorsalis ... -
Malpositioned and dislocated intraocular lenses : management, complications and surgical repositioning
(Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2023-04-06)Cataract surgery (exchange of the non-transparent crystalline lens with an IOL) is the most frequent surgery in Sweden, accounting for more than 130000 surgeries per year. Therefore, complications associated with cataract ... -
Biomarkers and psychological stress in amyotrophic lateral sclerosis
(Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2023-04-05)Amyotrophic lateral sclerosis (ALS) is a complex and progressive neurological disorder that causes a wide range of symptoms, including muscle weakness, mobility impairment, and marked functional decline. Unfortunately, ... -
Microvascular disease in cognitive impairment
(Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2023-04-05)Background: Cerebral small vessel disease has been recognized as the greatest vascular contributor to dementia. Previously, small vessel disease was thought to be part of normal aging. With more advanced imaging techniques, ... -
Healthcare when the bets are off : symptoms, trajectories and treatment of individuals with gambling disorder
(Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2023-03-28)Gambling Disorder is a debilitating condition associated with several adverse outcomes. Despite available treatment, most of those suffering never seek help and those that do often present a complex clinical picture with ... -
Bridging the gap between lipid dyshomeostasis and brain disorders : role of prosaposin and progranulin
(Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2023-01-26)Brain tissue is the second-highest lipid-containing tissue after adipose in the human body. Lipid homeostasis maintenance requires the coordination of multiple cellular organelles. Pathogenesis of brain disorders, especially ... -
Social influences on affective responses to negative experiences
(Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2023-01-25)As social human beings, the way we emotionally respond to what happens around us is often regulated by our interactions with others. The overall aim of this thesis is to advance the understanding of how social influences ... -
Compassionate mind training and its relationship with perceived stress, poor mental health, self-compassion and benevolence
(Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2023-01-20)Background: University students and employees are two populations where stress-related problems, anxiety, and depression are increasing. Interventions must be found to reverse this trajectory and to improve mental health. ... -
Identification of autoantigens in multiple sclerosis
(Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2023-01-04)Multiple sclerosis (MS) is an autoimmune disorder of the central nervous system in which cells from primarily the adaptive immune system infiltrate the brain and spinal cord, leading to inflammation and demyelination. ... -
Internet-based emotional awareness and expression therapy for functional somatic disorders
(Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2023-01-03)Background: Patients with Functional Somatic Disorders (FSD) make up one of the largest and most challenging patient groups in primary care. FSD are characterized by physical symptoms that have a major impact on the person’s ... -
Emotion regulation as a transdiagnostic construct : novel approaches to psychiatric diagnostics
(Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2022-12-12)Diagnostic co-occurrence among mental health problems is common. It has been suggested that more research which incorporates analysis on the symptom level and cuts across categorical diagnostic boundaries is needed. This ... -
The effectiveness and cost-effectiveness of cognitive behavioral therapy administered in group or via the internet for patients with irritable bowel syndrome
(Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2022-11-17)Background: Irritable Bowel Syndrome (IBS) is a benign but debilitating disorder. It is the most commonly diagnosed gastrointestinal condition and affects between 7-21% of the world’s population. It is characterized by ... -
It's the intention that matters : neural representations of learning from intentional harm in social interactions
(Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2022-11-17)As a social species, humans are not only driven by the pursuit of necessities such as food and shelter, but also complex processes such as social interactions. To navigate our everyday life, we use information gathered ... -
Experiences of signs and symptoms among men with advanced prostate cancer
(Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2022-11-15)Background: In the past decade, thanks to improved treatment options, many men with metastatic prostate cancer now survive longer than they would have before. The PSA value is often followed during the entire disease ...