Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience: Recent submissions
Now showing items 21-40 of 781
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Reduced variability of bursting activity during working memory
(Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2024-01-30)Working memories have long been thought to be maintained by persistent spiking. However, mounting evidence from multiple-electrode recording (and single-trial analyses) shows that the underlying spiking is better characterized ... -
Working memory control dynamics follow principles of spatial computing
(Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2024-01-30)Working memory (WM) allows us to remember and selectively control a limited set of items. Neural evidence suggests it is achieved by interactions between bursts of beta and gamma oscillations. However, it is not clear how ... -
Multimodal and multiscale brain networks : understanding aging, Alzheimer’s disease, and other neurodegenerative disorders
(Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2024-01-24)The human brain can be modeled as a complex network, often referred to as the connectome, where structural and functional connections govern its organization. Several neuroimaging studies have focused on understanding the ... -
From cytologic features to serum markers: advancing prognostication of uveal melanoma
(Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2024-01-08)Uveal melanoma (UM) is the most common primary intraocular malignancy in adults. As surveys show, almost all patients diagnosed with UM want prognostic information. However, the tools available today for early prognostication ... -
Genetic, neurodevelopmental and psychiatric studies of Turner syndrome
(Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2023-11-20)Turner Syndrome (TS) is a genetic condition characterized by the partial or complete loss of one sex chromosome. Associations with neurodevelopmental and psychiatric disorders has been suggested in TS, but findings are ... -
Respiratory influences on pupil size dynamics and visual recognition memory
(Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2023-11-16)Breathing, a fundamental rhythm of life, has traditionally been associated with the exchange of oxygen and carbon dioxide. However, recent research in both animal models and humans has unveiled additional roles of respiration ... -
Optimization of in vivo cell tracking methods with long-lived radionuclides for PET imaging
(Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2023-11-15)Stem cell transplantation and cell therapy are the standard treatments for many diseases; however, many suffer from complications, and the therapeutic efficiency can be challenging to predict. The off-target accumulation ... -
Self-assessed visual function in cataract surgery using Catquest-9SF
(Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2023-11-14)The cataract disease is the leading cause of preventable blindness in high-income countries alone as well as globally despite the groundbreaking technological advancements in recent years and steadily increasing number of ... -
The adolescent drinker : correlates and predictors of alcohol consumption among Swedish youth
(Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2023-11-06)Background: Drinking among adolescents has declined in most high-income countries during the past two decades. In Sweden, the reduction in youth drinking has been more pronounced than in many other parts of the world. The ... -
Treatment of alcohol dependence in primary care
(Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2023-10-12)Alcohol dependence is a common disorder and contributes to substantial morbidity and mortality globally. Only 10-20 percent engage in treatment, which makes alcohol dependence the mental disorder with the largest treatment ... -
Nonsuicidal self-injury in adolescence : attempts to improve and develop treatment
(Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2023-10-05)Nonsuicidal self-injury (NSSI) and NSSI disorder are common in adolescence and associated with adverse outcomes, including suicide attempts. Detecting vulnerable children and adolescents is essential to decrease the risk ... -
Controlled drinking : a viable treatment goal in alcohol use disorder?
(Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2023-09-25)Alcohol use disorders (AUD) has one of the largest treatment gaps among psychiatric diagnoses, with a treatment coverage of 10 to 20 %. One of the key contributing factors is the lack of treatments aiming for controlled ... -
Dual-energy imaging in stroke : feasibility of dual-layer detector cone-beam computed tomography
(Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2023-09-22)Background: Dual-energy computed tomography (DECT) is increasingly available and used in the standard diagnostic setting of ischemic stroke patients. For stroke patients with suspected large vessel occlusion, cone-beam ... -
Digital interventions to improve mental health and lifestyle behaviors for primary care patients
(Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2023-09-20)Background: Common mental health problems (CMHPs) give rise to large costs and much unnecessary suffering. Most patients with these problems are found in primary care. Positive effects of psychological treatment are well ... -
Inflammatory events and their effect on neural stem cell differentiation
(Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2023-09-08)Inflammation plays a dual role in the central nervous system (CNS), serving as a defence mechanism to protect and restore neural tissue following injuries or infections, but also driving degeneration and aggravating damage. ... -
Genetic, magnetic resonance imaging and body fluid biomarker associations with severity of multiple sclerosis
(Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2023-08-29)Multiple sclerosis is a chronic and progressive neuroinflammatory disease that leads to demyelination and neurodegeneration in the central nervous system (CNS). Previous research has identified a wide range of environmental, ... -
Supporting the supportive parents : community reinforcement and family training for families affected by alcohol or substance use
(Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2023-08-18)Background: Concerned significant others (CSOs) of individuals with problematic alcohol- or substance use show increased levels of psychiatric and somatic ill-health, social and economic problems and exposure to violence. ... -
Minimally invasive catheter-based technologies
(Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2023-08-10)A simple incision procedure in a blood vessel makes the entire vascular system accessible. Through contrast injection and X-ray visualization, the vascular tree can be mapped and navigated through manual manipulation of ... -
Activity restrictions, treatment and work disability among people with multiple sclerosis
(Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2023-07-28)Background: Multiple sclerosis (MS) is a disease that commonly occurs among individuals of working age. Its symptoms are heterogeneous and affect people with MS (PwMS) considerably in different aspects of their lives. ... -
From efficacy to implementation : applying internet-delivered cognitive behavioural therapy in the treatment of OCD
(Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2023-06-29)Background: Obsessive Compulsive Disorder (OCD) and Body Dysmorphic Disorder (BDD) are closely related psychiatric conditions associated with functional impairment across various life domains, an increased risk of suicide, ...