Licentiatavhandlingar / Licentiate Theses - H2 (BioNut)
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Recent submissions
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Characterization of brn1.2 and corticotropin-releasing hormone genes in zebrafish
(Biovetenskaper och näringslära / Biosciences and Nutrition, 2007-11-16)The zebrafish (Danio rerio), a tropical fresh water fish originally found in the rivers of India and Bangladesh has become a popular vertebrate model system over the last decade. The rapid sequencing of the zebrafish genome ... -
Role of estrogen receptor beta in mouse ventral prostate with relation to human prostatic diseases
(Biovetenskaper och näringslära / Biosciences and Nutrition, 2006-04-17)In this thesis we investigate role of estrogen receptor beta (ERbeta) in development and functioning of mouse ventral prostate, using it as a model for human extrapolations. ERbeta was discovered in 1995 and is a member ... -
Functional interaction studies of different transmembrane proteins, activities occurring in the pore membrane and in the inner nuclear membrane
(Inst för biovetenskaper och näringslära / Dept of Biosciences and Nutrition, 2012-11-01)Aim: The overall aim of my research has been to investigate protein‐protein interactions of nuclear envelope proteins. One specific aim has been to study the effect of mitotic phosphorylation on binding of the pore membrane ... -
Assessment of DNA damage, oxidative stress and inflammation in chronic kidney disease patients : and a clinical study of a dietary supplement
(Inst för biovetenskaper och näringslära / Dept of Biosciences and Nutrition, 2012-01-09)Decreased kidney function is associated with higher levels of oxidative stress, inflammation and malnutrition. Chronic kidney disease (CKD) patients have a higher risk to develop cardiovascular disease, atherosclerosis and ... -
Studies of histone modification systems in Schizosaccharomyces pombe
(Inst för biovetenskaper och näringslära / Dept of Biosciences and Nutrition, 2010-05-26)The genetic information in every cell is carried in the DNA. In eukaryotes the DNA is wrapped twice around proteins called histones forming a repeating unit called the nucleosome, in fibers known as chromatin. Nucleosomes ... -
Identification and evaluation of growth hormone antagonists
(Institutionen för medicinsk näringslära / Department of Medical Nutrition, 2005-08-08)States in which Growth hormone (GH) levels are elevated have been implicated in several physiological disorders such as acromegaly, diabetic complications and progression of malignancies. Classical treatments for acromegaly ... -
Oxidative DNA damage and other risk factors, in relation to lifestyle in diabetes type II and metabolic syndrome patients
(Biovetenskaper och näringslära / Biosciences and Nutrition, 2008-02-14)Lifestyle factors are important in prevention and treatment of lifestyle related diseases as obesity, type II diabetes and cardiovascular diseases. Patients with these diseases or in the risk zone of obtaining them are ... -
Studies on the phenotype of LXRβ-/- mice : from malabsorption to amyotrophic lateral sclerosis
(Biovetenskaper och näringslära / Biosciences and Nutrition, 2008-10-06)Liver X Receptors, LXRalpha and LXRbeta (NR1H2) are nuclear receptors belonging to the superfamily of ligand-activated transcription factors with a key role in the control of lipid and glucose metabolism. Studies of the ... -
Structure determination of Methanocaldococcus jannaschii nucleoside kinase
(Biovetenskaper och näringslära / Biosciences and Nutrition, 2005-09-22)All organisms can be divided into the tree kingdoms of life: Archaea, Bacteria and Eukarya. Archaeal organisms are often found to exhibit, compared to human perspectives, extreme environments, such as high temperature, ...